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Hepatitis C Virus RNA Replication Is Regulated by Host Geranylgeranylation and Fatty Acids

Hepatitis C Virus RNA Replication Is Regulated by Host Geranylgeranylation and Fatty Acids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0409834102

Hepatitis C Virus RNA Replication Is Regulated by Host Geranylgeranylation and Fatty Acids

About this item

Full title

Hepatitis C Virus RNA Replication Is Regulated by Host Geranylgeranylation and Fatty Acids

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (7), p.2561-2566

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Hepatitis C virus (HCV) infection is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Our laboratory has previously demonstrated that high-level HCV replication during acute infection of chimpanzees is associated with the modulation of multiple genes involved in lipid metabolism, and that drugs that regulate choles...

Alternative Titles

Full title

Hepatitis C Virus RNA Replication Is Regulated by Host Geranylgeranylation and Fatty Acids

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0409834102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0409834102

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0409834102

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