Characterization of Cells and Gene-Targeted Mice Deficient for the p53-Binding Kinase Homeodomain-In...
Characterization of Cells and Gene-Targeted Mice Deficient for the p53-Binding Kinase Homeodomain-Interacting Protein Kinase 1 (HIPK1)
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The tumor suppressor p53 is regulated in part by binding to cellular proteins. We used p53 as bait in the yeast two-hybrid system and isolated homeodomain-interacting protein kinase 1 (HIPK1) as a p53-binding protein. Deletion analysis showed that amino acids 100-370 of p53 and amino acids 885-1093 of HIPK1 were sufficient for HIPK1-p53 interaction...
Alternative Titles
Full title
Characterization of Cells and Gene-Targeted Mice Deficient for the p53-Binding Kinase Homeodomain-Interacting Protein Kinase 1 (HIPK1)
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_0530308100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0530308100
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0530308100
