Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided process...
Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
CD4⁺ and CD8⁺ T cell responses to endogenous retroviral envelope glycoprotein gp90 generate protective immunity to murine colon carcinoma CT26. A panel of I-Ad-restricted T cell hybridomas recognize gp90 synthesized by CT26 cells but not by other gp90-expressing tumors. Here we report that antigenicity resides in an incompletely folded form of gp90...
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Full title
Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing
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TN_cdi_crossref_primary_10_1073_pnas_0701307104
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0701307104
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0701307104
