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Executioner caspase-3 and caspase-7 are functionally distinct proteases

Executioner caspase-3 and caspase-7 are functionally distinct proteases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0707715105

Executioner caspase-3 and caspase-7 are functionally distinct proteases

About this item

Full title

Executioner caspase-3 and caspase-7 are functionally distinct proteases

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.12815-12819

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis. Because the major executioner caspases, caspase-3 and caspase-7, exhibit almost indistinguishable activity toward certain synthetic peptide substrates, this has led to the widespread view that these proteases...

Alternative Titles

Full title

Executioner caspase-3 and caspase-7 are functionally distinct proteases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0707715105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0707715105

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0707715105

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