Anemia and splenomegaly in cGKI-deficient mice
Anemia and splenomegaly in cGKI-deficient mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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To explore the functional significance of cGMP-dependent protein kinase type I (cGKI) in the regulation of erythrocyte survival, gene-targeted mice lacking cGKI were compared with their control littermates. By the age of 10 weeks, cGKI-deficient mice exhibited pronounced anemia and splenomegaly. Compared with control mice, the cGKI mutants had sign...
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Full title
Anemia and splenomegaly in cGKI-deficient mice
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TN_cdi_crossref_primary_10_1073_pnas_0708940105
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0708940105
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0708940105