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Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in...

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0802876105

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

About this item

Full title

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (27), p.9397-9402

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Emerging evidence suggests that myocyte enhancer factor 2 (MEF2) transcription factors act as effectors of neurogenesis in the brain, with MEF2C the predominant isoform in developing cerebrocortex. Here, we show that conditional knockout of Mef2c in nestin-expressing neural stem/progenitor cells (NSCs) impaired neuronal differentiation in vivo, res...

Alternative Titles

Full title

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0802876105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0802876105

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0802876105

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