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Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut mic...

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut mic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0804437105

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

About this item

Full title

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (36), p.13580-13585

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Bile salt hydrolases (BSHs) catalyze the "gateway" reaction in a wider pathway of bile acid modification by the gut microbiota. Because bile acids function as signaling molecules regulating their own biosynthesis, lipid absorption, cholesterol homeostasis, and local mucosal defenses in the intestine, microbial BSH activity has the potential to grea...

Alternative Titles

Full title

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0804437105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0804437105

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0804437105

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