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Heterogeneity of Natural Foxp3⁺ T Cells: A Committed Regulatory T-Cell Lineage and an Uncommitted Mi...

Heterogeneity of Natural Foxp3⁺ T Cells: A Committed Regulatory T-Cell Lineage and an Uncommitted Mi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0811556106

Heterogeneity of Natural Foxp3⁺ T Cells: A Committed Regulatory T-Cell Lineage and an Uncommitted Minor Population Retaining Plasticity

About this item

Full title

Heterogeneity of Natural Foxp3⁺ T Cells: A Committed Regulatory T-Cell Lineage and an Uncommitted Minor Population Retaining Plasticity

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1903-1908

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Natural regulatory T cells (${\rm{T}}_{{\rm{reg}}} $) represent a distinct lineage of T lymphocytes committed to suppressive functions, and expression of the transcription factor Foxp3 is thought to identify this lineage specifically. Here we report that whereas the majority of natural ${\rm{CD4}}^ + {\rm{Foxp3}}^ + $ T cells maintain stable Foxp3...

Alternative Titles

Full title

Heterogeneity of Natural Foxp3⁺ T Cells: A Committed Regulatory T-Cell Lineage and an Uncommitted Minor Population Retaining Plasticity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_0811556106

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0811556106

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0811556106

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