Spatio-Temporal Correlations Can Drastically Change the Response of a MAPK Pathway
Spatio-Temporal Correlations Can Drastically Change the Response of a MAPK Pathway
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Multisite covalent modification of proteins is omnipresent in eukaryotic cells. A well-known example is the mi tog en-activated protein kinase (MAPK) cascade where, in each layer of the cascade, a protein is phosphorylated at two sites. It has long been known that the response of a MAPK pathway strongly depends on whether the enzymes that modify th...
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Spatio-Temporal Correlations Can Drastically Change the Response of a MAPK Pathway
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TN_cdi_crossref_primary_10_1073_pnas_0906885107
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0906885107
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906885107