Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-...
Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion
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Publisher
National Academy of Sciences
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Language
English
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Publisher
National Academy of Sciences
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Scope and Contents
Contents
In healthy monocytes, Toll-like receptor (TLR) engagement induces production of reactive oxygen species (ROS), followed by an antioxidant response involved in IL-1β processing and secretion. Markers of the antioxidant response include intracellular thioredoxin and extracellular release of reduced cysteine. Cryopyrin-associated periodic syndromes (C...
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Full title
Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion
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TN_cdi_crossref_primary_10_1073_pnas_1000779107
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1000779107
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1000779107
