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Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1005101107

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

About this item

Full title

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15240-15245

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Circadian pacemaking requires the orderly synthesis, posttranslational modification, and degradation of clock proteins. In mammals, mutations in casein kinase 1 (CK1) ε or δ can alter the circadian period, but the particular functions of the WT isoforms within the pacemaker remain unclear. We selectively targeted WT CK1ε and CK1δ using pharmacologi...

Alternative Titles

Full title

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1005101107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1005101107

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1005101107

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