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Exposing malaria in-host diversity and estimating population diversity by capture-recapture using ma...

Exposing malaria in-host diversity and estimating population diversity by capture-recapture using ma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1007068107

Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing

About this item

Full title

Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (46), p.20138-20143

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Malaria infections commonly contain multiple genetically distinct variants. Mathematical and animal models suggest that interactions among these variants have a profound impact on the emergence of drug resistance. However, methods currently used for quantifying parasite diversity in individual infections are insensitive to low-abundance variants an...

Alternative Titles

Full title

Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1007068107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1007068107

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1007068107

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