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Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1010167107

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

About this item

Full title

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (49), p.21076-21081

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A growing body of evidence suggests that the multifunctional protein E4F1 is involved in signaling pathways that play essential roles during normal development and tumorigenesis. We generated E4F1 conditional knockout mice to address E4F1 functions in vivo in newborn and adult skin. E4F1 inactivation in the entire skin or in the basal compartment o...

Alternative Titles

Full title

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1010167107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1010167107

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1010167107

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