Single-molecule investigations of the stringent response machinery in living bacterial cells
Single-molecule investigations of the stringent response machinery in living bacterial cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The RelA-mediated stringent response is at the heart of bacterial adaptation to starvation and stress, playing a major role in the bacterial cell cycle and virulence. RelA integrates several environmental cues and synthesizes the alarmone ppGpp, which globally reprograms transcription, translation, and replication. We have developed and implemented...
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Single-molecule investigations of the stringent response machinery in living bacterial cells
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TN_cdi_crossref_primary_10_1073_pnas_1102255108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1102255108
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1102255108