Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally d...
Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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A single gram of soil is predicted to contain thousands of unique bacterial species. The majority of these species remain recalcitrant to standard culture methods, prohibiting their use as sources of unique bioactive small molecules. The cloning and analysis of DNA extracted directly from environmental samples (environmental DNA, eDNA) provides a m...
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Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
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TN_cdi_crossref_primary_10_1073_pnas_1103921108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1103921108
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1103921108