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Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally d...

Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1103921108

Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites

About this item

Full title

Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12629-12634

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A single gram of soil is predicted to contain thousands of unique bacterial species. The majority of these species remain recalcitrant to standard culture methods, prohibiting their use as sources of unique bioactive small molecules. The cloning and analysis of DNA extracted directly from environmental samples (environmental DNA, eDNA) provides a m...

Alternative Titles

Full title

Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1103921108

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1103921108

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1103921108

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