Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKB...
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells
About this item
Full title
Author / Creator
De Leon, Johanny Tonos , Iwai, Aki , Feau, Clementine , Garcia, Yenni , Balsiger, Heather A , Storer, Cheryl L , Suro, Raquel M , Garza, Kristine M , Lee, Sunmin , Sang Kim, Yeong , Chen, Yu , Ning, Yang-Min , Riggs, Daniel L , Fletterick, Robert J , Guy, R. Kiplin , Trepel, Jane B , Neckers, Leonard M and Cox, Marc B
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
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Scope and Contents
Contents
Drugs that target novel surfaces on the androgen receptor (AR) and/or novel AR regulatory mechanisms are promising alternatives for the treatment of castrate-resistant prostate cancer. The 52 kDa FK506 binding protein (FKBP52) is an important positive regulator of AR in cellular and whole animal models and represents an attractive target for the tr...
Alternative Titles
Full title
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1105160108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1105160108
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1105160108
