Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in...
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
About this item
Full title
Author / Creator
Lin, Wenchu , Cao, Jian , Liu, Jiayun , Beshiri, Michael L , Fujiwara, Yuko , Francis, Joshua , Cherniack, Andrew D , Geisen, Christoph , Blair, Lauren P , Zou, Mike R , Shen, Xiaohua , Kawamori, Dan , Liu, Zongzhi , Grisanzio, Chiara , Watanabe, Hideo , Minamishima, Yoji Andrew , Zhang, Qing , Kulkarni, Rohit N , Signoretti, Sabina , Rodig, Scott J , Bronson, Roderick T , Orkin, Stuart H , Tuck, David P , Benevolenskaya, Elizaveta V , Meyerson, Matthew , Kaelin, William G. Jr and Yan, Qin
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Aberrations in epigenetic processes, such as histone methylation, can cause cancer. Retinoblastoma binding protein 2 (RBP2; also called JARID1A or KDM5A) can demethylate tri- and dimethylated lysine 4 in histone H3, which are epigenetic marks for transcriptionally active chromatin, whereas the multiple endocrine neoplasia type 1 (MEN1) tumor suppre...
Alternative Titles
Full title
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
Authors, Artists and Contributors
Author / Creator
Cao, Jian
Liu, Jiayun
Beshiri, Michael L
Fujiwara, Yuko
Francis, Joshua
Cherniack, Andrew D
Geisen, Christoph
Blair, Lauren P
Zou, Mike R
Shen, Xiaohua
Kawamori, Dan
Liu, Zongzhi
Grisanzio, Chiara
Watanabe, Hideo
Minamishima, Yoji Andrew
Zhang, Qing
Kulkarni, Rohit N
Signoretti, Sabina
Rodig, Scott J
Bronson, Roderick T
Orkin, Stuart H
Tuck, David P
Benevolenskaya, Elizaveta V
Meyerson, Matthew
Kaelin, William G. Jr
Yan, Qin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1110104108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1110104108
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1110104108
