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Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of th...

Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of th...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1112838108

Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

About this item

Full title

Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20838-20843

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Pyrabactin resistance (PYR) 1 and its relatives belong to a family of soluble abscisic acid (ABA) receptors that inhibit type 2C protein phosphatases (PP2C) when in their agonist-stabilized conformation. Given their switch-like properties, we envisioned that mutations that stabilize their agonist-bound conformation could be used to activate signali...

Alternative Titles

Full title

Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1112838108

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1112838108

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1112838108

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