Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of th...
Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Pyrabactin resistance (PYR) 1 and its relatives belong to a family of soluble abscisic acid (ABA) receptors that inhibit type 2C protein phosphatases (PP2C) when in their agonist-stabilized conformation. Given their switch-like properties, we envisioned that mutations that stabilize their agonist-bound conformation could be used to activate signali...
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Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation
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TN_cdi_crossref_primary_10_1073_pnas_1112838108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1112838108
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1112838108