Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses ce...
Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility
About this item
Full title
Author / Creator
Friesland, Amy , Zhao, Yaxue , Chen, Yan-Hua , Wang, Lie , Zhou, Huchen and Lu, Qun
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Signaling through the Rho family of small GTPases has been intensely investigated for its crucial roles in a wide variety of human diseases. Although RhoA and Rac1 signaling pathways are frequently exploited with the aid of effective small molecule modulators, studies of the Cdc42 subclass have lagged because of a lack of such means. We have applie...
Alternative Titles
Full title
Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1116051110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1116051110
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1116051110
