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Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1201149109

Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

About this item

Full title

Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (10), p.3915-3920

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Diabetes is a pathological condition characterized by relative insulin deficiency, persistent hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. One therapeutic strategy is to amplify insulin-secretion capacity by increasing the number of the insulin-producing β cells without triggering a generalized proliferative response....

Alternative Titles

Full title

Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1201149109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1201149109

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1201149109

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