Structural insights into the editing of germ-line–encoded interactions between T-cell receptor and M...
Structural insights into the editing of germ-line–encoded interactions between T-cell receptor and MHC class II by Vα CDR3
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The conserved diagonal docking mode observed in structures of T-cell receptors (TCRs) bound to peptide–MHC ligands is believed to reflect coevolution of TCR and MHC genes. This coevolution is supported by the conservation of certain interactions between the germ-line–encoded complementarity-determining region (CDR)1 and CDR2 loops of TCR and MHC. H...
Alternative Titles
Full title
Structural insights into the editing of germ-line–encoded interactions between T-cell receptor and MHC class II by Vα CDR3
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TN_cdi_crossref_primary_10_1073_pnas_1207186109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1207186109
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1207186109
