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Runx3 and Runx1 Are Required for CD8 T Cell Development during Thymopoiesis

Runx3 and Runx1 Are Required for CD8 T Cell Development during Thymopoiesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1232420100

Runx3 and Runx1 Are Required for CD8 T Cell Development during Thymopoiesis

About this item

Full title

Runx3 and Runx1 Are Required for CD8 T Cell Development during Thymopoiesis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7731-7736

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The RUNX transcription factors are important regulators of lineage-specific gene expression. RUNX are bifunctional, acting both as activators and repressors of tissue-specific target genes. Recently, we have demonstrated that Runx3 is a neurogenic transcription factor, which regulates development and survival of proprioceptive neurons in dorsal roo...

Alternative Titles

Full title

Runx3 and Runx1 Are Required for CD8 T Cell Development during Thymopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1232420100

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1232420100

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1232420100

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