Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of...
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Large-scale proteomic approaches have identified numerous mitochondrial acetylated proteins; however in most cases, their regulation by acetyltransferases and deacetylases remains unclear. Sirtuin 3 (SIRT3) is an NAD ⁺-dependent mitochondrial protein deacetylase that has been shown to regulate a limited number of enzymes in key metabolic pathways....
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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
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TN_cdi_crossref_primary_10_1073_pnas_1302961110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1302961110
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1302961110