General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
To date, efforts to switch the cofactor specificity of oxidoreductases from nicotinamide adenine dinucleotide phosphate (NADPH) to nicotinamide adenine dinucleotide (NADH) have been made on a case-by-case basis with varying degrees of success. Here we present a straightforward recipe for altering the cofactor specificity of a class of NADPH-depende...
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Full title
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
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TN_cdi_crossref_primary_10_1073_pnas_1306073110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1306073110
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1306073110
