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Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c⁺ cells through TLR4

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c⁺ cells through TLR4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1306322110

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c⁺ cells through TLR4

About this item

Full title

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c⁺ cells through TLR4

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17444-17449

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Breast milk oligosaccharides shape the intestinal environment by affecting mucosal immunity and bacterial colonization. To clarify the role of milk oligosaccharide sialyl(α2,3)lactose (3SL) in intestinal physiology and disease, we investigated colitis development in Il10 ⁻/⁻ mice exposed to normal or 3SL-deficient milk during lactation. Onset and p...

Alternative Titles

Full title

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c⁺ cells through TLR4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1306322110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1306322110

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1306322110

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