Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacter...
Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
High-mobility group box 1 (HMGB1) is a DNA-binding protein abundantly expressed in the nucleus that has gained much attention for its regulation of immunity and inflammation. Despite this, whether and how HMGB1 contributes to protective and/or pathological responses in vivo is unclear. In this study, we constructed Hmgb1 -floxed (Hmgb1 ᶠ/ᶠ) mice to...
Alternative Titles
Full title
Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1320808110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1320808110
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1320808110
