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Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1322731111

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

About this item

Full title

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (3), p.1090-1095

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

E-cadherin is an important adhesion molecule whose loss is associated with progression and poor prognosis of liver cancer. However, it is unclear whether the loss of E-cadherin is a real culprit or a bystander in liver cancer progression. In addition, the precise role of E-cadherin in maintaining liver homeostasis is also still unknown, especially...

Alternative Titles

Full title

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1322731111

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1322731111

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1322731111

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