Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to pr...
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Thrombopoietin (TPO) acting via its receptor, the cellular homologue of the myeloproliferative leukemia virus oncogene (Mpl), is the major cytokine regulator of platelet number. To precisely define the role of specific hematopoietic cells in TPO-dependent hematopoiesis, we generated mice that express the Mpl receptor normally on stem/progenitor cel...
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Full title
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation
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TN_cdi_crossref_primary_10_1073_pnas_1404354111
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1404354111
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1404354111
