Nedd9 restrains renal cystogenesis in Pkd1⁻/⁻ mice
Nedd9 restrains renal cystogenesis in Pkd1⁻/⁻ mice
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Mutations inactivating the cilia-localized Pkd1 protein result in autosomal dominant polycystic kidney disease (ADPKD), a serious inherited syndrome affecting ∼1 in 500 people, in which accumulation of renal cysts eventually destroys kidney function. Severity of ADPKD varies throughout the population, for reasons thought to involve differences both...
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Full title
Nedd9 restrains renal cystogenesis in Pkd1⁻/⁻ mice
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1405362111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1405362111
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1405362111
