Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin
Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Significance Uncoupling protein 1 (UCP1) is a mitochondrial carrier protein responsible for thermogenesis in brown adipose tissue, and a putative therapeutic target for the treatment of obesity and related diseases. It is widely accepted that the protein is dimeric and regulated by binding one nucleotide per dimer, and unlike other mitochondrial ca...
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Full title
Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin
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Author / Creator
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1503833112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1503833112
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1503833112
