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Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(q...

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(q...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1509416112

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron–sulfur protein

About this item

Full title

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron–sulfur protein

Publisher

United States: National Acad Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (45), p.E6148-E6148

Language

English

Formats

Publication information

Publisher

United States: National Acad Sciences

More information

Scope and Contents

Contents

Mitochondria play an important role in numerous diseases as well as normative aging. Severe reduction in mitochondrial function contributes to childhood disorders such as Leigh Syndrome, whereas mild disruption can extend the lifespan of model organisms. The Caenorhabditis elegans isp-1 gene encodes the Rieske iron-sulfur protein subunit of cytochr...

Alternative Titles

Full title

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron–sulfur protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1509416112

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1509416112

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1509416112

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