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Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection

Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_151174198

Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection

About this item

Full title

Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (16), p.9226-9230

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Normal levels of CD4+regulatory T cells are critical for the maintenance of immunological homeostasis and the prevention of autoimmune diseases. However, we now show that the expansion of CD4+regulatory T cells in response to a chronic viral infection can lead to immunosuppression. Mice persistently infected with Friend retrovirus develop approxima...

Alternative Titles

Full title

Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_151174198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_151174198

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.151174198

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