Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection
Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Normal levels of CD4+regulatory T cells are critical for the maintenance of immunological homeostasis and the prevention of autoimmune diseases. However, we now show that the expansion of CD4+regulatory T cells in response to a chronic viral infection can lead to immunosuppression. Mice persistently infected with Friend retrovirus develop approxima...
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Full title
Immunosuppression by CD4+Regulatory T Cells Induced by Chronic Retroviral Infection
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TN_cdi_crossref_primary_10_1073_pnas_151174198
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_151174198
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.151174198