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Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1513988112

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

About this item

Full title

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (38), p.11923-11928

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Whole-genome amplification (WGA) for next-generation sequencing has seen wide applications in biology and medicine when characterization of the genome of a single cell is required. High uniformity and fidelity of WGA is needed to accurately determine genomic variations, such as copy number variations (CNVs) and single-nucleotide variations (SNVs)....

Alternative Titles

Full title

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1513988112

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1513988112

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1513988112

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