Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies
Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Despite progress in systemic small interfering RNA (siRNA) delivery to the liver and to solid tumors, systemic siRNA delivery to leukocytes remains challenging. The ability to silence gene expression in leukocytes has great potential for identifying drug targets and for RNAi-based therapy for leukocyte diseases. However, both normal and malignant l...
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Full title
Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies
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TN_cdi_crossref_primary_10_1073_pnas_1519273113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1519273113
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1519273113