Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype...
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
About this item
Full title
Author / Creator
Tripathi, Satyendra C. , Peters, Haley L. , Taguchi, Ayumu , Katayama, Hiroyuki , Wang, Hong , Momin, Amin , Jolly, Mohit Kumar , Celiktas, Muge , Rodriguez-Canales, Jaime , Liu, Hui , Behrens, Carmen , Wistuba, Ignacio I. , Ben-Jacob, Eshel , Levine, Herbert , Molldrem, Jeffrey J. , Hanash, Samir M. and Ostrin, Edwin J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The immunoproteasome plays a key role in generation of HLA peptides for T cell-mediated immunity. Integrative genomic and proteomic analysis of non-small cell lung carcinoma (NSCLC) cell lines revealed significantly reduced expression of immunoproteasome components and their regulators associated with epithelial to mesenchymal transition. Low expre...
Alternative Titles
Full title
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_1521812113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1521812113
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1521812113
