Large-conductance Ca 2+ - and voltage-gated K + channels form and break interactions with membrane l...
Large-conductance Ca 2+ - and voltage-gated K + channels form and break interactions with membrane lipids during each gating cycle
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United States
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English
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United States
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Membrane depolarization and intracellular Ca
promote activation of the large-conductance Ca
- and voltage-gated (Slo1) big potassium (BK) channel. We examined the physical interactions that stabilize the closed and open conformations of the ion conduction gate of the human Slo1 channel using electrophysiological and computational approaches....
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Full title
Large-conductance Ca 2+ - and voltage-gated K + channels form and break interactions with membrane lipids during each gating cycle
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TN_cdi_crossref_primary_10_1073_pnas_1901381116
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1901381116
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1901381116
