Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake
Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake
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Author / Creator
Publisher
United States
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Language
English
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Publisher
United States
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Scope and Contents
Contents
Ca
uptake by mitochondria regulates bioenergetics, apoptosis, and Ca
signaling. The primary pathway for mitochondrial Ca
uptake is the mitochondrial calcium uniporter (MCU), a Ca
-selective ion channel in the inner mitochondrial membrane. MCU-mediated Ca
uptake is driven by the sizable inner-membrane potential generated by the electr...
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Full title
Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake
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TN_cdi_crossref_primary_10_1073_pnas_2005976117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2005976117
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2005976117