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Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2005976117

Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

About this item

Full title

Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

Publisher

United States

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21731-21739

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Ca
uptake by mitochondria regulates bioenergetics, apoptosis, and Ca
signaling. The primary pathway for mitochondrial Ca
uptake is the mitochondrial calcium uniporter (MCU), a Ca
-selective ion channel in the inner mitochondrial membrane. MCU-mediated Ca
uptake is driven by the sizable inner-membrane potential generated by the electr...

Alternative Titles

Full title

Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_2005976117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2005976117

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2005976117

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