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Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy

Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2009786117

Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy

About this item

Full title

Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy

Publisher

United States

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (37), p.23096-23105

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

The β
-adrenergic receptor (β
AR) is a prototypical G protein-coupled receptor (GPCR) that preferentially couples to the stimulatory G protein G
and stimulates cAMP formation. Functional studies have shown that the β
AR also couples to inhibitory G protein G
, activation of which inhibits cAMP formation [R. P. Xiao, Sci. STKE
, re...

Alternative Titles

Full title

Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_2009786117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2009786117

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2009786117

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