Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy
Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy
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United States
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Language
English
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United States
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Contents
The β
-adrenergic receptor (β
AR) is a prototypical G protein-coupled receptor (GPCR) that preferentially couples to the stimulatory G protein G
and stimulates cAMP formation. Functional studies have shown that the β
AR also couples to inhibitory G protein G
, activation of which inhibits cAMP formation [R. P. Xiao, Sci. STKE
, re...
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Full title
Analysis of β 2 AR-G s and β 2 AR-G i complex formation by NMR spectroscopy
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TN_cdi_crossref_primary_10_1073_pnas_2009786117
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2009786117
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2009786117