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Organ-Specific and Systemic Autoimmune Diseases Originate from Defects in Hematopoietic Stem Cells

Organ-Specific and Systemic Autoimmune Diseases Originate from Defects in Hematopoietic Stem Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_87_21_8341

Organ-Specific and Systemic Autoimmune Diseases Originate from Defects in Hematopoietic Stem Cells

About this item

Full title

Organ-Specific and Systemic Autoimmune Diseases Originate from Defects in Hematopoietic Stem Cells

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1990-11, Vol.87 (21), p.8341-8344

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Transplantation of bone marrow cells from nonobese diabetic (NOD) mice, a model for type 1 diabetes mellitus, to C3H/HeN mice, which express I-Eα molecules and have aspartic acid at residue 57 of the I-Aβchain, induced insulitis followed by overt diabetes in the recipient C3H/HeN mice more than 40 weeks after bone marrow transplantation. When cyclo...

Alternative Titles

Full title

Organ-Specific and Systemic Autoimmune Diseases Originate from Defects in Hematopoietic Stem Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_87_21_8341

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_87_21_8341

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.87.21.8341

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