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Excess Brain Protein Oxidation and Enzyme Dysfunction in Normal Aging and in Alzheimer Disease

Excess Brain Protein Oxidation and Enzyme Dysfunction in Normal Aging and in Alzheimer Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_88_23_10540

Excess Brain Protein Oxidation and Enzyme Dysfunction in Normal Aging and in Alzheimer Disease

About this item

Full title

Excess Brain Protein Oxidation and Enzyme Dysfunction in Normal Aging and in Alzheimer Disease

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (23), p.10540-10543

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

The relationship between Alzheimer disease (AD) and aging is not currently known. In this study, postmortem frontal- and occipital-pole brain samples were obtained from 16 subjects with AD, 8 age-matched controls, and 5 young controls. These samples were analyzed both for protein oxidation products (carbonyl) and the activities of two enzymes vulne...

Alternative Titles

Full title

Excess Brain Protein Oxidation and Enzyme Dysfunction in Normal Aging and in Alzheimer Disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_88_23_10540

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_88_23_10540

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.88.23.10540

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