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Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I

Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_91_14_6486

Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I

About this item

Full title

Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1994-07, Vol.91 (14), p.6486-6490

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Grb2 is a 25-kDa adaptor protein composed of a Src homology 2 (SH2) domain and two flanking Src homology 3 (SH3) domains. One function of Grb2 is to couple tyrosine-phosphorylated proteins (through its SH2 domain) to downstream effectors (through its SH3 domains). Using an overlay assay, we have identified four major Grb2-binding proteins in synapt...

Alternative Titles

Full title

Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_91_14_6486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_91_14_6486

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.91.14.6486

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