A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persis...
A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persistent and Acute Infections of Mice with Lymphocytic Choriomeningitis Virus: Implications for Adoptive Immunotherapy of Virus Carriers
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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This study demonstrates that neutralizing-antibody-producing B cells, CD4+ T cells, and interferons (IFNs) are of key importance in virus control both in adoptive immunotherapy of persistent infection and in the late phase of acute infection with the WE strain of lymphocytic choriomeningitis virus (LCMV). We report the following results. (i) Cleara...
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Full title
A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persistent and Acute Infections of Mice with Lymphocytic Choriomeningitis Virus: Implications for Adoptive Immunotherapy of Virus Carriers
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TN_cdi_crossref_primary_10_1073_pnas_94_13_6874
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_94_13_6874
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.13.6874