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A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persis...

A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_94_13_6874

A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persistent and Acute Infections of Mice with Lymphocytic Choriomeningitis Virus: Implications for Adoptive Immunotherapy of Virus Carriers

About this item

Full title

A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persistent and Acute Infections of Mice with Lymphocytic Choriomeningitis Virus: Implications for Adoptive Immunotherapy of Virus Carriers

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1997-06, Vol.94 (13), p.6874-6879

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

This study demonstrates that neutralizing-antibody-producing B cells, CD4+ T cells, and interferons (IFNs) are of key importance in virus control both in adoptive immunotherapy of persistent infection and in the late phase of acute infection with the WE strain of lymphocytic choriomeningitis virus (LCMV). We report the following results. (i) Cleara...

Alternative Titles

Full title

A Critical Role for Neutralizing-Antibody-Producing B Cells, CD4+ T Cells, and Interferons in Persistent and Acute Infections of Mice with Lymphocytic Choriomeningitis Virus: Implications for Adoptive Immunotherapy of Virus Carriers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_94_13_6874

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_94_13_6874

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.94.13.6874

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