The Role of Transmembrane Domain 2 in Cation Transport by the Na-K-Cl Cotransporter
The Role of Transmembrane Domain 2 in Cation Transport by the Na-K-Cl Cotransporter
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
The human and shark Na-K-Cl cotransporters (NKCC), although 74% identical in amino acid sequence, exhibit marked differences in ion transport and bumetanide binding. We have utilized shark-human chimeras of NKCC1 to search for regions that confer the kinetic differences. Two chimeras (hs3.1 and its reverse sh3.1) with a junction point located at th...
Alternative Titles
Full title
The Role of Transmembrane Domain 2 in Cation Transport by the Na-K-Cl Cotransporter
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_95_12_7179
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_95_12_7179
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.95.12.7179
