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Bax Directly Induces Release of Cytochrome c from Isolated Mitochondria

Bax Directly Induces Release of Cytochrome c from Isolated Mitochondria

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_95_9_4997

Bax Directly Induces Release of Cytochrome c from Isolated Mitochondria

About this item

Full title

Bax Directly Induces Release of Cytochrome c from Isolated Mitochondria

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1998-04, Vol.95 (9), p.4997-5002

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Bax is a pro-apoptotic member of the Bcl-2 protein family that resides in the outer mitochondrial membrane. It is controversial whether Bax promotes cell death directly through its putative function as a channel protein versus indirectly by inhibiting cellular regulators of the cell death proteases (caspases). We show here that addition of submicro...

Alternative Titles

Full title

Bax Directly Induces Release of Cytochrome c from Isolated Mitochondria

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_95_9_4997

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_95_9_4997

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.95.9.4997

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