Dipeptidyl Peptidase I Is Required for the Processing and Activation of Granzymes A and B in vivo
Dipeptidyl Peptidase I Is Required for the Processing and Activation of Granzymes A and B in vivo
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
Dipeptidyl peptidase I (DPPI) is a lysosomal cysteine protease that has been implicated in the processing of granzymes, which are neutral serine proteases exclusively expressed in the granules of activated cytotoxic lymphocytes. In this report, we show that cytotoxic lymphocytes derived from DPPI-/- mice contain normal amounts of granzymes A and B,...
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Full title
Dipeptidyl Peptidase I Is Required for the Processing and Activation of Granzymes A and B in vivo
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TN_cdi_crossref_primary_10_1073_pnas_96_15_8627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_96_15_8627
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.96.15.8627
