Neuromelanin Biosynthesis Is Driven by Excess Cytosolic Catecholamines Not Accumulated by Synaptic V...
Neuromelanin Biosynthesis Is Driven by Excess Cytosolic Catecholamines Not Accumulated by Synaptic Vesicles
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Melanin, the pigment in hair, skin, eyes, and feathers, protects external tissue from damage by UV light. In contrast, neuromelanin (NM) is found in deep brain regions, specifically in loci that degenerate in Parkinson's disease. Although this distribution suggests a role for NM in Parkinson's disease neurodegeneration, the biosynthesis and functio...
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Full title
Neuromelanin Biosynthesis Is Driven by Excess Cytosolic Catecholamines Not Accumulated by Synaptic Vesicles
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TN_cdi_crossref_primary_10_1073_pnas_97_22_11869
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_97_22_11869
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.22.11869
