Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole
Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole
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Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
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Publisher
England: Taylor & Francis
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Scope and Contents
Contents
The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by the use of amorphous solid dispersions. Phase diagrams of ABZ-polymer binary mixtures generated from Flory-Huggins theory were used to assess miscibility and processability. Forced degradation studies showed that ABZ degraded upon exposure to hydrogen peroxi...
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Full title
Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole
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Record Identifier
TN_cdi_crossref_primary_10_1080_03639045_2016_1220577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_03639045_2016_1220577
Other Identifiers
ISSN
0363-9045
E-ISSN
1520-5762
DOI
10.1080/03639045.2016.1220577