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Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_03639045_2016_1220577

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

About this item

Full title

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

Publisher

England: Taylor & Francis

Journal title

Drug development and industrial pharmacy, 2017-05, Vol.43 (5), p.797-811

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by the use of amorphous solid dispersions. Phase diagrams of ABZ-polymer binary mixtures generated from Flory-Huggins theory were used to assess miscibility and processability. Forced degradation studies showed that ABZ degraded upon exposure to hydrogen peroxi...

Alternative Titles

Full title

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1080_03639045_2016_1220577

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_03639045_2016_1220577

Other Identifiers

ISSN

0363-9045

E-ISSN

1520-5762

DOI

10.1080/03639045.2016.1220577

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