Eplerenone nanocrystals engineered by controlled crystallization for enhanced oral bioavailability
Eplerenone nanocrystals engineered by controlled crystallization for enhanced oral bioavailability
About this item
Full title
Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
Formats
Publication information
Publisher
England: Taylor & Francis
Subjects
More information
Scope and Contents
Contents
Poor aqueous solubility of eplerenone (EPL) is a major obstacle to achieve sufficient bioavailability after oral administration. In this study, we aimed to develop and evaluate eplerenone nanocrystals (EPL-NCs) for solubility and dissolution enhancement. D-optimal combined mixture process using Design-Expert software was employed to generate differ...
Alternative Titles
Full title
Eplerenone nanocrystals engineered by controlled crystallization for enhanced oral bioavailability
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1080_10717544_2021_2008051
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_10717544_2021_2008051
Other Identifiers
ISSN
1071-7544
E-ISSN
1521-0464
DOI
10.1080/10717544.2021.2008051
