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Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through...

Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2163996

Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation

About this item

Full title

Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation

Publisher

England: Taylor & Francis

Journal title

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2163996-2163996

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

In the present study, 5-arylidene rhodanine derivatives 3a-f, N-glucosylation rhodanine 6, S-glucosylation rhodanine 7, N-glucoside rhodanine 8 and S-glucosylation 5-arylidene rhodanines 13a-c were synthesised and screened for cytotoxicity against a panel of cancer cells with investigating the effective molecular target and mechanistic cell death....

Alternative Titles

Full title

Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1080_14756366_2022_2163996

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2163996

Other Identifiers

ISSN

1475-6366

E-ISSN

1475-6374

DOI

10.1080/14756366.2022.2163996

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