PK10453, a nonselective platelet-derived growth factor receptor inhibitor, prevents the progression...
PK10453, a nonselective platelet-derived growth factor receptor inhibitor, prevents the progression of pulmonary arterial hypertension
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Publisher
London, England: University of Chicago Press
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Language
English
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Publisher
London, England: University of Chicago Press
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Scope and Contents
Contents
The platelet-derived growth factor (PDGF) signaling pathway has been found to be activated in human pulmonary arterial hypertension (PAH) and in animal models of the disease. Our study tested the hypothesis that a novel, nonselective inhaled PDGF receptor inhibitor, PK10453, would decrease pulmonary hypertension both in the rat monocrotaline (MCT)...
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Full title
PK10453, a nonselective platelet-derived growth factor receptor inhibitor, prevents the progression of pulmonary arterial hypertension
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Record Identifier
TN_cdi_crossref_primary_10_1086_674881
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1086_674881
Other Identifiers
ISSN
2045-8932,2045-8940
E-ISSN
2045-8940
DOI
10.1086/674881
